Atomistic Insights into Regulatory Mechanisms of the HER2 Tyrosine Kinase Domain: A Molecular Dynamics Study

Por Telesco, Shannon E., Radhakrishnan, Ravi
Publicado em 2009

Structural Systems Biology and Multiscale Signaling Models

Por Telesco, Shannon E., Radhakrishnan, Ravi
Publicado no Ann Biomed Eng (2012)

Molecular Modeling of the ErbB4/HER4 Kinase in the Context of the HER4 Signaling Network Helps Rationalize the Effects of Clinically Identified HER4 Somatic Mutations on the Cell P...

Por Telesco, Shannon E., Vadigepalli, Rajanikanth, Radhakrishnan, Ravi
Publicado em 2013

Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases

Por Shih, Andrew J., Telesco, Shannon E., Radhakrishnan, Ravi
Publicado em 2011

Investigating Molecular Mechanisms of Activation and Mutation of the HER2 Receptor Tyrosine Kinase through Computational Modeling and Simulation

Por Telesco, Shannon E., Shih, Andrew, Liu, Yingting, Radhakrishnan, Ravi
Publicado em 2011

A multiscale modeling approach to investigate molecular mechanisms of pseudokinase activation and drug resistance in the HER3/ErbB3 receptor tyrosine kinase signaling network

Por Telesco, Shannon E., Shih, Andrew J., Jia, Fei, Radhakrishnan, Ravi
Publicado em 2011

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

Por Shi, Fumin, Telesco, Shannon E., Liu, Yingting, Radhakrishnan, Ravi, Lemmon, Mark A.
Publicado em 2010

Molecular Dynamics Analysis of Conserved Hydrophobic and Hydrophilic Bond Interaction Networks in ErbB Family Kinases

Por Shih, Andrew J., Telesco, Shannon E., Choi, Sung Hee, Lemmon, Mark A., Radhakrishnan, Ravi
Publicado em 2011

Fecal Microbiota Signatures Are Associated with Response to Ustekinumab Therapy among Crohn’s Disease Patients

Por Doherty, Matthew K., Ding, Tao, Koumpouras, Charlie, Telesco, Shannon E., Monast, Calixte, Das, Anuk, Brodmerkel, Carrie, Schloss, Patrick D.
Publicado no mBio (2018)

High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors

Por Di Narzo, Antonio F., Telesco, Shannon E., Brodmerkel, Carrie, Argmann, Carmen, Peters, Lauren A., Li, Katherine, Kidd, Brian, Dudley, Joel, Cho, Judy, Schadt, Eric E., Kasarskis, Andrew, Dobrin, Radu, Hao, Ke
Publicado no PLoS Genet (2017)

A functional genomics predictive network model identifies regulators of inflammatory bowel disease

Por Peters, Lauren A, Perrigoue, Jacqueline, Mortha, Arthur, Iuga, Alina, Song, Won-min, Neiman, Eric M, Llewellyn, Sean R, Di Narzo, Antonio, Kidd, Brian A, Telesco, Shannon E, Zhao, Yongzhong, Stojmirovic, Aleksandar, Sendecki, Jocelyn, Shameer, Khader, Miotto, Riccardo, Losic, Bojan, Shah, Hardik, Lee, Eunjee, Wang, Minghui, Faith, Jeremiah J, Kasarskis, Andrew, Brodmerkel, Carrie, Curran, Mark, Das, Anuk, Friedman, Joshua R, Fukui, Yoshinori, Humphrey, Mary Beth, Iritani, Brian M, Sibinga, Nicholas, Tarrant, Teresa K, Argmann, Carmen, Hao, Ke, Roussos, Panos, Zhu, Jun, Zhang, Bin, Dobrin, Radu, Mayer, Lloyd F, Schadt, Eric E
Publicado no Nat Genet (2017)