Loading...

Atomistic Insights into Regulatory Mechanisms of the HER2 Tyrosine Kinase Domain: A Molecular Dynamics Study

HER2 (ErbB2/Neu) is a receptor tyrosine kinase belonging to the epidermal growth factor receptor (EGFR)/ErbB family and is overexpressed in 20–30% of human breast cancers. Although several crystal structures of ErbB kinases have been solved, the precise mechanism of HER2 activation remains unknown,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Telesco, Shannon E., Radhakrishnan, Ravi
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907720/
https://ncbi.nlm.nih.gov/pubmed/19289058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3912
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!