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Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases

The ErbB/EGFR/HER family of kinases consists of four homologous receptor tyrosine kinases which are important regulatory elements in many cellular processes, including cell proliferation, differentiation, and migration. Somatic mutations in, or over-expression of, the ErbB family is found in many ca...

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Hlavní autoři: Shih, Andrew J., Telesco, Shannon E., Radhakrishnan, Ravi
Médium: Artigo
Jazyk:Inglês
Vydáno: Molecular Diversity Preservation International (MDPI) 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119571/
https://ncbi.nlm.nih.gov/pubmed/21701703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers3011195
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