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Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases

The ErbB/EGFR/HER family of kinases consists of four homologous receptor tyrosine kinases which are important regulatory elements in many cellular processes, including cell proliferation, differentiation, and migration. Somatic mutations in, or over-expression of, the ErbB family is found in many ca...

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Detalhes bibliográficos
Main Authors: Shih, Andrew J., Telesco, Shannon E., Radhakrishnan, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119571/
https://ncbi.nlm.nih.gov/pubmed/21701703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers3011195
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