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Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases

The ErbB/EGFR/HER family of kinases consists of four homologous receptor tyrosine kinases which are important regulatory elements in many cellular processes, including cell proliferation, differentiation, and migration. Somatic mutations in, or over-expression of, the ErbB family is found in many ca...

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書目詳細資料
Main Authors: Shih, Andrew J., Telesco, Shannon E., Radhakrishnan, Ravi
格式: Artigo
語言:Inglês
出版: Molecular Diversity Preservation International (MDPI) 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119571/
https://ncbi.nlm.nih.gov/pubmed/21701703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers3011195
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