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ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation
ErbB3/HER3 is one of four members of the human epidermal growth factor receptor (EGFR/HER) or ErbB receptor tyrosine kinase family. ErbB3 binds neuregulins via its extracellular region and signals primarily by heterodimerizing with ErbB2/HER2/Neu. A recently appreciated role for ErbB3 in resistance...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867849/ https://ncbi.nlm.nih.gov/pubmed/20351256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002753107 |
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