GI Research Path: From Academia to the Pharmaceutical Industry

Por Friedman, Joshua R.
Publicado no Cell Mol Gastroenterol Hepatol (2016)

A role for microRNA in cystic liver and kidney diseases

Por Chu, Andrew S., Friedman, Joshua R.
Publicado em 2008

miR-122 regulates hepatic lipid metabolism and tumor suppression

Por Wen, Jessica, Friedman, Joshua R.
Publicado em 2012

On the origin of the liver

Por Friedman, Joshua R., Kaestner, Klaus H.
Publicado em 2011

Novel targets of miR-30, a microRNA required for biliary development

Por Le Guen, Claire L., Friedman, Joshua R., Hand, Nicholas J.
Publicado em 2013

Hepatic function is preserved in the absence of mature microRNAs

Por Hand, Nicholas J., Master, Zankhana R., Le Lay, John, Friedman, Joshua R.
Publicado em 2009

Circulating MicroRNA is a Biomarker of Biliary Atresia

Por Zahm, Adam M., Hand, Nicholas J., Boateng, LaTasha A., Friedman, Joshua R.
Publicado em 2012

Transcriptional Networks in the Liver: Hepatocyte Nuclear Factor 6 Function Is Largely Independent of Foxa2

Por Rubins, Nir E., Friedman, Joshua R., Le, Phillip P., Zhang, Liping, Brestelli, John, Kaestner, Klaus H.
Publicado em 2005

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development

Por Gao, Nan, LeLay, John, Vatamaniuk, Marko Z., Rieck, Sebastian, Friedman, Joshua R., Kaestner, Klaus H.
Publicado em 2008

MicroRNAs Control Intestinal Epithelial Differentiation, Architecture, and Barrier Function

Por McKenna, Lindsay B., Schug, Jonathan, Friedman, Joshua R., McKenna, Jaime B, Kaestner, Klaus H.
Publicado em 2010

Extra-Hepatic Cholangiocyte Cilia are Abnormal in Biliary Atresia

Por Karjoo, Sara, Hand, Nicholas J., Loarca, Lorena, Russo, Pierre A., Friedman, Joshua R., Wells, Rebecca G.
Publicado em 2013

Circulating MicroRNA Is a Biomarker of Pediatric Crohn Disease

Por Zahm, Adam M., Thayu, Meena, Hand, Nicholas J., Horner, Amber, Leonard, Mary B., Friedman, Joshua R.
Publicado em 2011

Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in ER stress

Por Bochkis, Irina M., Rubins, Nir E., White, Peter, Furth, Emma E., Friedman, Joshua R., Kaestner, Klaus H.
Publicado em 2008

Foxa2 regulates multiple pathways of insulin secretion

Por Lantz, Kristen A., Vatamaniuk, Marko Z., Brestelli, John E., Friedman, Joshua R., Matschinsky, Franz M., Kaestner, Klaus H.
Publicado em 2004

The microRNA-30 family is required for vertebrate hepatobiliary development

Por Hand, Nicholas J., Master, Zankhana R., EauClaire, Steven F., Weinblatt, Daniel E., Matthews, Randolph P., Friedman, Joshua R.
Publicado em 2008

Rectal microRNAs are perturbed in pediatric inflammatory bowel disease of the colon

Por Zahm, Adam M., Hand, Nicholas J., Tsoucas, Daphne M., Le Guen, Claire L., Baldassano, Robert N., Friedman, Joshua R.
Publicado em 2014

Glucocorticoid Receptor-Dependent Gene Regulatory Networks

Por Phuc Le, Phillip, Friedman, Joshua R, Schug, Jonathan, Brestelli, John E, Parker, J. Brandon, Bochkis, Irina M, Kaestner, Klaus H
Publicado em 2005

MicroRNA profiling identifies miR-29 as a regulator of disease-associated pathways in experimental biliary atresia

Por Hand, Nicholas J., Horner, Amber M., Master, Zankhana R., Boateng, LaTasha A., LeGuen, Claire, Uvaydova, Marina, Friedman, Joshua R.
Publicado em 2012

Pediatric eosinophilic esophagitis is associated with changes in esophageal microRNAs

Por Zahm, Adam M., Menard-Katcher, Calies, Benitez, Alain J., Tsoucas, Daphne M., Le Guen, Claire L., Hand, Nicholas J., Friedman, Joshua R.
Publicado em 2014

Orthogonal analysis of C/EBPβ targets in vivo during liver proliferation

Por Friedman, Joshua R., Larris, Brian, Le, Phillip P., Peiris, T. Harshani, Arsenlis, Athanasios, Schug, Jonathan, Tobias, John W., Kaestner, Klaus H., Greenbaum, Linda E.
Publicado em 2004