Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development

The onset of pancreas development in the foregut endoderm is marked by activation of the homeobox gene Pdx1 (IPF1). Pdx1 is essential for the expansion of the pancreatic primordium and the development of endocrine islets. The control of Pdx1 expression has been only partially elucidated. We demonstr...

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Detalhes bibliográficos
Main Authors: Gao, Nan, LeLay, John, Vatamaniuk, Marko Z., Rieck, Sebastian, Friedman, Joshua R., Kaestner, Klaus H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607077/
https://ncbi.nlm.nih.gov/pubmed/19141476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1752608
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