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Foxa1 and Foxa2 are Essential for Sexual Dimorphism in Liver Cancer

Hepatocellular carcinoma (HCC) is sexually dimorphic in both rodents and humans, with significantly higher incidence in males, an effect that is dependent on sex hormones. The molecular mechanisms by which estrogens prevent and androgens promote liver cancer remain unclear. Here, we discover that se...

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Autors principals: Li, Zhaoyu, Tuteja, Geetu, Schug, Jonathan, Kaestner, Klaus H.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266536/
https://ncbi.nlm.nih.gov/pubmed/22265403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.11.026
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