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Foxa1 and Foxa2 are Essential for Sexual Dimorphism in Liver Cancer

Hepatocellular carcinoma (HCC) is sexually dimorphic in both rodents and humans, with significantly higher incidence in males, an effect that is dependent on sex hormones. The molecular mechanisms by which estrogens prevent and androgens promote liver cancer remain unclear. Here, we discover that se...

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Detalhes bibliográficos
Main Authors: Li, Zhaoyu, Tuteja, Geetu, Schug, Jonathan, Kaestner, Klaus H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266536/
https://ncbi.nlm.nih.gov/pubmed/22265403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.11.026
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