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Foxa2 regulates multiple pathways of insulin secretion

The regulation of insulin secretion by pancreatic β cells is perturbed in several diseases, including adult-onset (type 2) diabetes and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). The first mouse model for PHHI has a conditional deletion of the gene encoding the winged-helix transcri...

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Detalhes bibliográficos
Main Authors: Lantz, Kristen A., Vatamaniuk, Marko Z., Brestelli, John E., Friedman, Joshua R., Matschinsky, Franz M., Kaestner, Klaus H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC503770/
https://ncbi.nlm.nih.gov/pubmed/15314688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421149
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