Transcriptional Networks in the Liver: Hepatocyte Nuclear Factor 6 Function Is Largely Independent of Foxa2

A complex network of hepatocyte nuclear transcription factors, including HNF6 and Foxa2, regulates the expression of liver-specific genes. The current model, based on in vitro studies, suggests that HNF6 and Foxa2 interact physically. This interaction is thought to synergistically stimulate Foxa2-de...

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Detalhes bibliográficos
Main Authors: Rubins, Nir E., Friedman, Joshua R., Le, Phillip P., Zhang, Liping, Brestelli, John, Kaestner, Klaus H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190247/
https://ncbi.nlm.nih.gov/pubmed/16055718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7069-7077.2005
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