Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer

por Samala, Ramakrishna, Thorsheim, Helen R., Goda, Satyanarayana, Taskar, Kunal, Gril, Brunilde, Steeg, Patricia S., Smith, Quentin R.
Publicado en Pharm Res (2016)

Unmasking the Role of Uptake Transporters for Digoxin Uptake Across the Barriers of the Central Nervous System in Rat

por Taskar, Kunal S, Mariappan, T Thanga, Kurawattimath, Vishwanath, Singh Gautam, Shashyendra, Radhakrishna Mullapudi, TV, Sridhar, Srikanth K, Kallem, Raja Reddy, Marathe, Punit, Mandlekar, Sandhya
Publicado en J Cent Nerv Syst Dis (2017)

Uptake of ANG1005, a Novel Paclitaxel Derivative, Through the Blood-Brain Barrier into Brain and Experimental Brain Metastases of Breast Cancer

por Thomas, Fancy C., Taskar, Kunal, Rudraraju, Vinay, Goda, Satyanarayana, Thorsheim, Helen R., Gaasch, Julie A., Palmieri, Diane, Steeg, Patricia S., Lockman, Paul R., Smith, Quentin R.
Publicado 2009

Intestinal P-gp and Putative Hepatic OATP1B Induction: ITC Perspective on Drug Development Implications

por Zamek-Gliszczynski, Maciej J., Patel, Mitesh, Yang, Xinning, Lutz, Justin D., Chu, Xiaoyan, Brouwer, Kim L. R., Lai, Yurong, Lee, Caroline A., Neuhoff, Sibylle, Paine, Mary F., Sugiyama, Yuichi, Taskar, Kunal S., Galetin, Aleksandra
Publicado en Clin Pharmacol Ther (2020)

Heterogeneous Blood-Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer

por Lockman, Paul R., Mittapalli, Rajendar K., Taskar, Kunal S., Rudraraju, Vinay, Gril, Brunilde, Bohn, Kaci A., Adkins, Chris E., Roberts, Amanda, Thorsheim, Helen R., Gaasch, Julie A., Huang, Suyun, Palmieri, Diane, Steeg, Patricia S., Smith, Quentin R.
Publicado 2010

Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer

por Taskar, Kunal S., Rudraraju, Vinay, Mittapalli, Rajendar K., Samala, Ramakrishna, R. Thorsheim, Helen, Lockman, Julie, Gril, Brunilde, Hua, Emily, Palmieri, Diane, Polli, Joseph W., Castellino, Stephen, Rubin, Stephen D., Lockman, Paul R., Steeg, Patricia S., Smith, Quentin R.
Publicado 2011

Physiologically‐Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug–Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Reco...

por Taskar, Kunal S., Pilla Reddy, Venkatesh, Burt, Howard, Posada, Maria M., Varma, Manthena, Zheng, Ming, Ullah, Mohammed, Emami Riedmaier, Arian, Umehara, Ken‐ichi, Snoeys, Jan, Nakakariya, Masanori, Chu, Xiaoyan, Beneton, Maud, Chen, Yuan, Huth, Felix, Narayanan, Rangaraj, Mukherjee, Dwaipayan, Dixit, Vaishali, Sugiyama, Yuichi, Neuhoff, Sibylle
Publicado en Clin Pharmacol Ther (2019)

Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

por Kenna, J. Gerry, Taskar, Kunal S., Battista, Christina, Bourdet, David L., Brouwer, Kim L.R., Brouwer, Kenneth R., Dai, David, Funk, Christoph, Hafey, Michael J., Lai, Yurong, Maher, Jonathan, Pak, Y. Anne, Pedersen, Jenny M., Polli, Joseph W., Rodrigues, A. David, Watkins, Paul B., Yang, Kyunghee, Yucha, Robert W.
Publicado en Clin Pharmacol Ther (2018)

Vorinostat Inhibits Brain Metastatic Colonization in a Model of Triple-Negative Breast Cancer and Induces DNA Double-Strand Breaks

por Palmieri, Diane, Lockman, Paul R., Thomas, Fancy C., Hua, Emily, Herring, Jeanne, Hargrave, Elizabeth, Johnson, Matthew, Flores, Natasha, Qian, Yongzhen, Vega-Valle, Eleazar, Taskar, Kunal S., Rudraraju, Vinay, Mittapalli, Rajendar K., Gaasch, Julie A., Bohn, Kaci A., Thorsheim, Helen R., Liewehr, David J., Davis, Sean, Reilly, John F., Walker, Robert, Bronder, Julie L., Feigenbaum, Lionel, Steinberg, Seth M., Camphausen, Kevin, Meltzer, Paul S., Richon, Victoria M., Smith, Quentin R., Steeg, Patricia S.
Publicado en Clin Cancer Res (2009)