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Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer

PURPOSE: To evaluate vinorelbine drug exposure and activity in brain metastases of the human MDA-MB-231BR breast cancer model using integrated imaging and analysis. METHODS: Brain and systemic metastases were created by administration of cancer cells in female NuNu mice. After metastases developed,...

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Publicado en:Pharm Res
Main Authors: Samala, Ramakrishna, Thorsheim, Helen R., Goda, Satyanarayana, Taskar, Kunal, Gril, Brunilde, Steeg, Patricia S., Smith, Quentin R.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818344/
https://ncbi.nlm.nih.gov/pubmed/27541873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-016-2012-3
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