Molecular determinants of blood–brain barrier permeation

Por Geldenhuys, Werner J, Mohammad, Afroz S, Adkins, Chris E, Lockman, Paul R
Publicado no Ther Deliv (2015)

Inhibition of VEGF and Angiopoietin-2 to Reduce Brain Metastases of Breast Cancer Burden

Por Bohn, Kaci A., Adkins, Chris E., Nounou, Mohamed I., Lockman, Paul R.
Publicado no Front Pharmacol (2017)

Quantitative fluorescence microscopy provides high resolution imaging of passive diffusion and P-gp mediated efflux at the in vivo blood–brain barrier

Por Mittapalli, Rajendar K., Manda, Vamshi K., Bohn, Kaci A., Adkins, Chris E., Lockman, Paul R.
Publicado no J Neurosci Methods (2013)

Impact of L-DOPA treatment on regional cerebral blood flow and metabolism in the basal ganglia in a rat model of Parkinson's disease

Por Ohlin, K. Elisabet, Sebastianutto, Irene, Adkins, Chris E., Lundblad, Cornelia, Lockman, Paul R., Cenci, M. Angela
Publicado no Neuroimage (2012)

Quantitative fluorescent microscopy measures vascular pore size in primary and metastatic brain tumors

Por Mittapalli, Rajendar K, Adkins, Chris E, Bohn, Kaci. A., Mohammad, Afroz, Lockman, Julie A, Lockman, Paul R
Publicado no Cancer Res (2016)

A novel preclinical method to quantitatively evaluate early-stage metastatic events at the murine blood-brain barrier

Por Adkins, Chris E, Nounou, Mohamed I, Mittapalli, Rajendar K, Terrell-Hall, Tori B, Mohammad, Afroz S, Jagannathan, Rajaganapathi, Lockman, Paul R
Publicado no Cancer Prev Res (Phila) (2014)

Characterization of passive permeability at the blood-tumor barrier in five preclinical models of brain metastases of breast cancer

Por Adkins, Chris E., Mohammad, Afroz S., Terrell-Hall, Tori, Dolan, Emma L., Shah, Neal, Sechrest, Emily, Griffith, Jessica, Lockman, Paul R.
Publicado no Clin Exp Metastasis (2016)

NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

Por Adkins, Chris E., Nounou, Mohamed I., Hye, Tanvirul, Mohammad, Afroz S., Terrell-Hall, Tori, Mohan, Neel K., Eldon, Michael A., Hoch, Ute, Lockman, Paul R.
Publicado no BMC Cancer (2015)

Anti-cancer antibody trastuzumab-melanotransferrin conjugate (BT2111) for the treatment of metastatic HER2+ breast cancer tumors in the brain: An in-vivo study

Por Nounou, Mohamed Ismail, Adkins, Chris E., Rubinchik, Evelina, Terrell-Hall, Tori B, Afroz, Mohamed, Vitalis, Tim, Gabathuler, Reinhard, Tian, Mei Mei, Lockman, Paul R.
Publicado no Pharm Res (2016)

Semi-automated Rapid Quantification of Brain Vessel Density Utilizing Fluorescent Microscopy

Por Bohn, Kaci A., Adkins, Chris E., Mittapalli, Rajendar K., Terrell-Hall, Tori B., Mohammad, Afroz S., Shah, Neal, Dolan, Emma L., Nounou, Mohamed I., Lockman, Paul R.
Publicado no J Neurosci Methods (2016)

P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model

Por Adkins, Chris E., Mittapalli, Rajendar K., Manda, Vamshi K., Nounou, Mohamed I., Mohammad, Afroz S., Terrell, Tori B., Bohn, Kaci A., Yasemin, Celik, Grothe, Tiffany R., Lockman, Julie A., Lockman, Paul R.
Publicado em 2013

Novel treatment strategies for brain tumors and metastases

Por El-Habashy, Salma E., Nazief, Alaa M., Adkins, Chris E., Wen, Ming Ming, El-Kamel, Amal H., Hamdan, Ahmed M., Hanafy, Amira S., Terrell, Tori O., Mohammad, Afroz S., Lockman, Paul R., Nounou, Mohamed Ismail
Publicado no Pharm Pat Anal (2014)

Heterogeneous Blood-Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer

Por Lockman, Paul R., Mittapalli, Rajendar K., Taskar, Kunal S., Rudraraju, Vinay, Gril, Brunilde, Bohn, Kaci A., Adkins, Chris E., Roberts, Amanda, Thorsheim, Helen R., Gaasch, Julie A., Huang, Suyun, Palmieri, Diane, Steeg, Patricia S., Smith, Quentin R.
Publicado em 2010

Alterations in Pericyte Subpopulations are Associated with Elevated Blood-Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer

Por Lyle, L. Tiffany, Lockman, Paul R., Adkins, Chris E., Mohammad, Afroz Shareef, Sechrest, Emily, Hua, Emily, Palmieri, Diane, Liewehr, David J., Steinberg, Seth M., Kloc, Wojciech, Izycka-Swieszewska, Ewa, Duchnowska, Renata, Nayyar, Naema, Brastianos, Priscilla K., Steeg, Patricia S., Gril, Brunilde
Publicado no Clin Cancer Res (2016)