Neuron-glia interaction in neuroinflammation

Por Suzumura, Akio., Ikenaka, Kazuhiro.
Publicado em 2013

Sweepers in the CNS: Microglial Migration and Phagocytosis in the Alzheimer Disease Pathogenesis

Por Noda, Mariko, Suzumura, Akio
Publicado em 2012

Gap junctions and hemichannels composed of connexins: potential therapeutic targets for neurodegenerative diseases

Por Takeuchi, Hideyuki, Suzumura, Akio
Publicado em 2014

Interleukin-19 Acts as a Negative Autocrine Regulator of Activated Microglia

Por Horiuchi, Hiroshi, Parajuli, Bijay, Wang, Yue, Azuma, Yasu-Taka, Mizuno, Tetsuya, Takeuchi, Hideyuki, Suzumura, Akio
Publicado no PLoS One (2015)

Fractalkine Attenuates Excito-neurotoxicity via Microglial Clearance of Damaged Neurons and Antioxidant Enzyme Heme Oxygenase-1 Expression

Por Noda, Mariko, Doi, Yukiko, Liang, Jianfeng, Kawanokuchi, Jun, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Mizuno, Tetsuya, Suzumura, Akio
Publicado em 2011

Interleukin-34 Selectively Enhances the Neuroprotective Effects of Microglia to Attenuate Oligomeric Amyloid-β Neurotoxicity

Por Mizuno, Tetsuya, Doi, Yukiko, Mizoguchi, Hiroyuki, Jin, Shijie, Noda, Mariko, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Suzumura, Akio
Publicado em 2011

GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia

Por Parajuli, Bijay, Sonobe, Yoshifumi, Kawanokuchi, Jun, Doi, Yukiko, Noda, Mariko, Takeuchi, Hideyuki, Mizuno, Tetsuya, Suzumura, Akio
Publicado em 2012

FGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway

Por Noda, Mariko, Takii, Kento, Parajuli, Bijay, Kawanokuchi, Jun, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Mizuno, Tetsuya, Suzumura, Akio
Publicado em 2014

Fractalkine attenuates excito-neurotoxicity via microglial clearance of damaged neurons and antioxidant enzyme heme oxygenase-1 expression.

Por Noda, Mariko, Doi, Yukiko, Liang, Jianfeng, Kawanokuchi, Jun, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Mizuno, Tetsuya, Suzumura, Akio
Publicado no J Biol Chem (2016)

Evidence for Aberrant Astrocyte Hemichannel Activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)

Por Burkovetskaya, Maria, Karpuk, Nikolay, Xiong, Juan, Bosch, Megan, Boska, Michael D., Takeuchi, Hideyuki, Suzumura, Akio, Kielian, Tammy
Publicado em 2014

Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation

Por Watanabe, Mitsuru, Masaki, Katsuhisa, Yamasaki, Ryo, Kawanokuchi, Jun, Takeuchi, Hideyuki, Matsushita, Takuya, Suzumura, Akio, Kira, Jun-ichi
Publicado no Sci Rep (2016)

The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity

Por Li Endong, Noda Mariko, Doi Yukiko, Parajuli Bijay, Kawanokuchi Jun, Sonobe Yoshifumi, Takeuchi Hideyuki, Mizuno Tetsuya, Suzumura Akio
Publicado em 2012-06-01

The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity

Por Li, Endong, Noda, Mariko, Doi, Yukiko, Parajuli, Bijay, Kawanokuchi, Jun, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Mizuno, Tetsuya, Suzumura, Akio
Publicado em 2012

Interleukin-34 Restores Blood–Brain Barrier Integrity by Upregulating Tight Junction Proteins in Endothelial Cells

Por Jin, Shijie, Sonobe, Yoshifumi, Kawanokuchi, Jun, Horiuchi, Hiroshi, Cheng, Yi, Wang, Yue, Mizuno, Tetsuya, Takeuchi, Hideyuki, Suzumura, Akio
Publicado no PLoS One (2014)

Disruption of GM2/GD2 synthase gene resulted in overt expression of 9-O-acetyl GD3 irrespective of Tis211

Por Furukawa, Keiko, Aixinjueluo, Wei, Kasama, Takeshi, Ohkawa, Yuki, Yoshihara, Michiko, Ohmi, Yusuke, Tajima, Orie, Suzumura, Akio, Kittaka, Daiji, Furukawa, Koichi
Publicado em 2008

Microglia Activated with the Toll-Like Receptor 9 Ligand CpG Attenuate Oligomeric Amyloid β Neurotoxicity in in Vitro and in Vivo Models of Alzheimer’s Disease

Por Doi, Yukiko, Mizuno, Tetsuya, Maki, Yuki, Jin, Shijie, Mizoguchi, Hiroyuki, Ikeyama, Masayoshi, Doi, Minoru, Michikawa, Makoto, Takeuchi, Hideyuki, Suzumura, Akio
Publicado em 2009

Fingolimod Phosphate Attenuates Oligomeric Amyloid β–Induced Neurotoxicity via Increased Brain-Derived Neurotrophic Factor Expression in Neurons

Por Doi, Yukiko, Takeuchi, Hideyuki, Horiuchi, Hiroshi, Hanyu, Taketo, Kawanokuchi, Jun, Jin, Shijie, Parajuli, Bijay, Sonobe, Yoshifumi, Mizuno, Tetsuya, Suzumura, Akio
Publicado em 2013

Interleukin-1β Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes

Por Wang, Yue, Jin, Shijie, Sonobe, Yoshifumi, Cheng, Yi, Horiuchi, Hiroshi, Parajuli, Bijay, Kawanokuchi, Jun, Mizuno, Tetsuya, Takeuchi, Hideyuki, Suzumura, Akio
Publicado em 2014

Interleukin-25 Expressed by Brain Capillary Endothelial Cells Maintains Blood-Brain Barrier Function in a Protein Kinase Cϵ-dependent Manner

Por Sonobe, Yoshifumi, Takeuchi, Hideyuki, Kataoka, Kunio, Li, Hua, Jin, Shijie, Mimuro, Maya, Hashizume, Yoshio, Sano, Yasuteru, Kanda, Takashi, Mizuno, Tetsuya, Suzumura, Akio
Publicado em 2009

Granulocyte-Colony Stimulating Factor Attenuates Oligomeric Amyloid β Neurotoxicity by Activation of Neprilysin

Por Doi, Yukiko, Takeuchi, Hideyuki, Mizoguchi, Hiroyuki, Fukumoto, Kazuya, Horiuchi, Hiroshi, Jin, Shijie, Kawanokuchi, Jun, Parajuli, Bijay, Sonobe, Yoshifumi, Mizuno, Tetsuya, Suzumura, Akio
Publicado em 2014