Fractalkine Attenuates Excito-neurotoxicity via Microglial Clearance of Damaged Neurons and Antioxidant Enzyme Heme Oxygenase-1 Expression

Glutamate-induced excito-neurotoxicity likely contributes to non-cell autonomous neuronal death in neurodegenerative diseases. Microglial clearance of dying neurons and associated debris is essential to maintain healthy neural networks in the central nervous system. In fact, the functions of microgl...

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Detalhes bibliográficos
Main Authors: Noda, Mariko, Doi, Yukiko, Liang, Jianfeng, Kawanokuchi, Jun, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Mizuno, Tetsuya, Suzumura, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023525/
https://ncbi.nlm.nih.gov/pubmed/21071446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.169839
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