FGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway

BACKGROUND: The accumulation of activated microglia is a hallmark of various neurodegenerative diseases. Microglia may have both protective and toxic effects on neurons through the production of various soluble factors, such as chemokines. Indeed, various chemokines mediate the rapid and accurate mi...

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Bibliografiske detaljer
Main Authors: Noda, Mariko, Takii, Kento, Parajuli, Bijay, Kawanokuchi, Jun, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Mizuno, Tetsuya, Suzumura, Akio
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022102/
https://ncbi.nlm.nih.gov/pubmed/24735639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-76
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