FGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway

BACKGROUND: The accumulation of activated microglia is a hallmark of various neurodegenerative diseases. Microglia may have both protective and toxic effects on neurons through the production of various soluble factors, such as chemokines. Indeed, various chemokines mediate the rapid and accurate mi...

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Bibliografiset tiedot
Päätekijät: Noda, Mariko, Takii, Kento, Parajuli, Bijay, Kawanokuchi, Jun, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Mizuno, Tetsuya, Suzumura, Akio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2014
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022102/
https://ncbi.nlm.nih.gov/pubmed/24735639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-76
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