Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord

Por Ohmi, Yuhsuke, Ohkawa, Yuki, Tajima, Orie, Sugiura, Yasuo, Furukawa, Keiko, Furukawa, Koichi
Publicado em 2014

Ganglioside GD3 induces convergence and synergism of adhesion and hepatocyte growth factor/Met signals in melanomas

Por Furukawa, Keiko, Kambe, Mariko, Miyata, Maiko, Ohkawa, Yuki, Tajima, Orie, Furukawa, Koichi
Publicado no Cancer Sci (2014)

Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues

Por Ohmi, Yuhsuke, Tajima, Orie, Ohkawa, Yuki, Mori, Atsushi, Sugiura, Yasuo, Furukawa, Keiko, Furukawa, Koichi
Publicado em 2009

Expression of B4GALNT1, an essential glycosyltransferase for the synthesis of complex gangliosides, suppresses BACE1 degradation and modulates APP processing

Por Yamaguchi, Tokiaki, Yamauchi, Yoshio, Furukawa, Keiko, Ohmi, Yuhsuke, Ohkawa, Yuki, Zhang, Qing, Okajima, Tetsuya, Furukawa, Koichi
Publicado no Sci Rep (2016)

Disruption of GM2/GD2 synthase gene resulted in overt expression of 9-O-acetyl GD3 irrespective of Tis211

Por Furukawa, Keiko, Aixinjueluo, Wei, Kasama, Takeshi, Ohkawa, Yuki, Yoshihara, Michiko, Ohmi, Yusuke, Tajima, Orie, Suzumura, Akio, Kittaka, Daiji, Furukawa, Koichi
Publicado em 2008

Ganglioside GD3 Enhances Adhesion Signals and Augments Malignant Properties of Melanoma Cells by Recruiting Integrins to Glycolipid-enriched Microdomains

Por Ohkawa, Yuki, Miyazaki, Sayaka, Hamamura, Kazunori, Kambe, Mariko, Miyata, Maiko, Tajima, Orie, Ohmi, Yuhsuke, Yamauchi, Yoshio, Furukawa, Koichi, Furukawa, Keiko
Publicado em 2010

Neogenin, Defined as a GD3-associated Molecule by Enzyme-mediated Activation of Radical Sources, Confers Malignant Properties via Intracytoplasmic Domain in Melanoma Cells

Por Kaneko, Kei, Ohkawa, Yuki, Hashimoto, Noboru, Ohmi, Yuhsuke, Kotani, Norihiro, Honke, Koichi, Ogawa, Mitsutaka, Okajima, Tetsuya, Furukawa, Keiko, Furukawa, Koichi
Publicado no J Biol Chem (2016)

Functional Activation of Src Family Kinase Yes Protein Is Essential for the Enhanced Malignant Properties of Human Melanoma Cells Expressing Ganglioside GD3

Por Hamamura, Kazunori, Tsuji, Momoko, Hotta, Hiroshi, Ohkawa, Yuki, Takahashi, Masataka, Shibuya, Hidenobu, Nakashima, Hideyuki, Yamauchi, Yoshio, Hashimoto, Noboru, Hattori, Hisashi, Ueda, Minoru, Furukawa, Keiko, Furukawa, Koichi
Publicado em 2011

Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase

Por Ohkawa, Yuki, Momota, Hiroyuki, Kato, Akira, Hashimoto, Noboru, Tsuda, Yusuke, Kotani, Norihiro, Honke, Koichi, Suzumura, Akio, Furukawa, Keiko, Ohmi, Yuhsuke, Natsume, Atsushi, Wakabayashi, Toshihiko, Furukawa, Koichi
Publicado no J Biol Chem (2015)

Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis

Por Ohmi, Yuhsuke, Ise, Wataru, Harazono, Akira, Takakura, Daisuke, Fukuyama, Hidehiro, Baba, Yoshihiro, Narazaki, Masashi, Shoda, Hirofumi, Takahashi, Nobunori, Ohkawa, Yuki, Ji, Shuting, Sugiyama, Fumihiro, Fujio, Keishi, Kumanogoh, Atsushi, Yamamoto, Kazuhiko, Kawasaki, Nana, Kurosaki, Tomohiro, Takahashi, Yoshimasa, Furukawa, Koichi
Publicado no Nat Commun (2016)