Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase

There have been a few studies on the ganglioside expression in human glioma tissues. However, the role of these gangliosides such as GD3 and GD2 has not been well understood. In this study we employed a genetically engineered mouse model of glioma to clarify the functions of GD3 in gliomas. Forced e...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Ohkawa, Yuki, Momota, Hiroyuki, Kato, Akira, Hashimoto, Noboru, Tsuda, Yusuke, Kotani, Norihiro, Honke, Koichi, Suzumura, Akio, Furukawa, Keiko, Ohmi, Yuhsuke, Natsume, Atsushi, Wakabayashi, Toshihiko, Furukawa, Koichi
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Glycobiology and Extracellular Matrices
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481208/
https://ncbi.nlm.nih.gov/pubmed/25940087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.635755
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