Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase

There have been a few studies on the ganglioside expression in human glioma tissues. However, the role of these gangliosides such as GD3 and GD2 has not been well understood. In this study we employed a genetically engineered mouse model of glioma to clarify the functions of GD3 in gliomas. Forced e...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Ohkawa, Yuki, Momota, Hiroyuki, Kato, Akira, Hashimoto, Noboru, Tsuda, Yusuke, Kotani, Norihiro, Honke, Koichi, Suzumura, Akio, Furukawa, Keiko, Ohmi, Yuhsuke, Natsume, Atsushi, Wakabayashi, Toshihiko, Furukawa, Koichi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481208/
https://ncbi.nlm.nih.gov/pubmed/25940087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.635755
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