Osteoporosis Therapy: Bone Modeling during Growth and Aging

Por Sugiyama, Toshihiro, Oda, Hiromi
Publicado no Front Endocrinol (Lausanne) (2017)

Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones

Por Sugiyama, Toshihiro, Price, Joanna S., Lanyon, Lance E.
Publicado em 2010

Mechanical Loading-Related Bone Gain Is Enhanced by Tamoxifen but Unaffected by Fulvestrant in Female Mice

Por Sugiyama, Toshihiro, Galea, Gabriel L., Lanyon, Lance E., Price, Joanna S.
Publicado em 2010

Potential role of p53 mutation in chemical hepatocarcinogenesis of rats

Por Deng, Wei-Guo, Fu, Yan, Li, Yu-Lin, Sugiyama, Toshihiro
Publicado no World J Gastroenterol (2004)

Deficiency of β1‐6 N‐Acetylglucosaminyltransferase Involved in the Biosynthesis of Blood Group I Antigen in the Liver of LEC Rats

Por Gu, Jianguo, Nishikawa, Atsushi, Matsuura, Nariaki, Sugiyama, Toshihiro, Taniguchi, Naoyuki
Publicado no Jpn J Cancer Res (1992)

Romosozumab and Blosozumab: Alternative Drugs of Mechanical Strain-Related Stimulus Toward a Cure for Osteoporosis

Por Sugiyama, Toshihiro, Torio, Tetsuya, Miyajima, Tsuyoshi, Kim, Yoon Taek, Oda, Hiromi
Publicado no Front Endocrinol (Lausanne) (2015)

TGF-β1 expression is up-regulated in maturation stage enamel organ and may induce ameloblast apoptosis

Por Tsuchiya, Masahiro, Sharma, Ramaswamy, Tye, Coralee E., Sugiyama, Toshihiro, Bartlett, John D.
Publicado em 2009

Taste of Milk from Inflamed Breasts of Breastfeeding Mothers with Mastitis Evaluated Using a Taste Sensor

Por Yoshida, Michiko, Shinohara, Hitomi, Sugiyama, Toshihiro, Kumagai, Masanori, Muto, Hajime, Kodama, Hideya
Publicado em 2014

The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells

Por Sasabe, Tetsuo, Maeda, Shinichiro, Kishida, Kenichi, Yamano, Mariko, Miwa, Yoshihiro, Sugiyama, Toshihiro
Publicado no Drug Metab Lett (2016)

Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the o...

Por Saxon, Leanne K., Jackson, Brendan F., Sugiyama, Toshihiro, Lanyon, Lance E., Price, Joanna S.
Publicado em 2011

Age-Related Impairment of Bones' Adaptive Response to Loading in Mice Is Associated With Sex-Related Deficiencies in Osteoblasts but No Change in Osteocytes†

Por Meakin, Lee B, Galea, Gabriel L, Sugiyama, Toshihiro, Lanyon, Lance E, Price, Joanna S
Publicado no J Bone Miner Res (2014)

Improvement of Skeletal Fragility by Teriparatide in Adult Osteoporosis Patients: A Novel Mechanostat-Based Hypothesis for Bone Quality

Por Sugiyama, Toshihiro, Torio, Tetsuya, Sato, Tsuyoshi, Matsumoto, Masahito, Kim, Yoon Taek, Oda, Hiromi
Publicado no Front Endocrinol (Lausanne) (2015)

Enhancing Effect of a Choline–deficient Diet on Alterations of Hepatic Drug–metabolizing Enzymes in Hepatitis– and Hepatoma–predisposed Rats (LEC Rats)

Por Sugiyama, Toshihiro, Matsunaga, Mikako, Jain, Suresh K., Jain, Sadhana, Ikeda, Yoshitaka, Taniguchi, Naoyuki
Publicado no Jpn J Cancer Res (1991)

Proteomic analysis identifies proteins that continue to grow hepatic stem-like cells without differentiation

Por Saheki, Toshihiko, Ito, Hitomi, Sekiguchi, Akihiro, Nishina, Atsuyoshi, Sugiyama, Toshihiro, Izumi, Takashi, Kojima, Itaru
Publicado em 2008

Bones' Adaptive Response to Mechanical Loading Is Essentially Linear Between the Low Strains Associated With Disuse and the High Strains Associated With the Lamellar/Woven Bone Tra...

Por Sugiyama, Toshihiro, Meakin, Lee B, Browne, William J, Galea, Gabriel L, Price, Joanna S, Lanyon, Lance E
Publicado em 2012

Ameloblastin in Hertwig’s Epithelial Root Sheath Regulates Tooth Root Formation and Development

Por Hirose, Naoto, Shimazu, Atsushi, Watanabe, Mineo, Tanimoto, Kotaro, Koyota, Souichi, Sugiyama, Toshihiro, Uchida, Takashi, Tanne, Kazuo
Publicado em 2013

Male mice housed in groups engage in frequent fighting and show a lower response to additional bone loading than females or individually housed males that do not fight

Por Meakin, Lee B., Sugiyama, Toshihiro, Galea, Gabriel L., Browne, William J., Lanyon, Lance E., Price, Joanna S.
Publicado em 2013

Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4

Por Galea, Gabriel L., Sunters, Andrew, Meakin, Lee B., Zaman, Gul, Sugiyama, Toshihiro, Lanyon, Lance E., Price, Joanna S.
Publicado em 2011

MiR-153 Regulates Amelogenesis by Targeting Endocytotic and Endosomal/lysosomal Pathways–Novel Insight into the Origins of Enamel Pathologies

Por Yin, Kaifeng, Lin, Wenting, Guo, Jing, Sugiyama, Toshihiro, Snead, Malcolm L., Hacia, Joseph G., Paine, Michael L.
Publicado no Sci Rep (2017)

Cadmium-coordinated supramolecule suppresses tumor growth of T-cell leukemia in mice

Por Zhou, Xiaoping, Koizumi, Yukio, Zhang, Muxin, Natsui, Miyuki, Koyota, Souichi, Yamada, Manabu, Kondo, Yoshihiko, Hamada, Fumio, Sugiyama, Toshihiro
Publicado no Cancer Sci (2015)