Enhancing Effect of a Choline–deficient Diet on Alterations of Hepatic Drug–metabolizing Enzymes in Hepatitis– and Hepatoma–predisposed Rats (LEC Rats)

Marked alterations of hepatic drug–metabolizing enzymes were observed in hepatitis– and hepatoma–predisposed rats (LEC rats) fed a choline–deficient diet. The diet enhanced the development of hepatitis with severe jaundice. The levels of two major classes of cytochrome P–450, P–450(PB) and P–450(MC)...

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Publicat a:Jpn J Cancer Res
Autors principals: Sugiyama, Toshihiro, Matsunaga, Mikako, Jain, Suresh K., Jain, Sadhana, Ikeda, Yoshitaka, Taniguchi, Naoyuki
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 1991
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918451/
https://ncbi.nlm.nih.gov/pubmed/1904419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01861.x
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