Enhancing Effect of a Choline–deficient Diet on Alterations of Hepatic Drug–metabolizing Enzymes in Hepatitis– and Hepatoma–predisposed Rats (LEC Rats)

Marked alterations of hepatic drug–metabolizing enzymes were observed in hepatitis– and hepatoma–predisposed rats (LEC rats) fed a choline–deficient diet. The diet enhanced the development of hepatitis with severe jaundice. The levels of two major classes of cytochrome P–450, P–450(PB) and P–450(MC)...

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Détails bibliographiques
Publié dans:Jpn J Cancer Res
Auteurs principaux: Sugiyama, Toshihiro, Matsunaga, Mikako, Jain, Suresh K., Jain, Sadhana, Ikeda, Yoshitaka, Taniguchi, Naoyuki
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 1991
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918451/
https://ncbi.nlm.nih.gov/pubmed/1904419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01861.x
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