Enhancing Effect of a Choline–deficient Diet on Alterations of Hepatic Drug–metabolizing Enzymes in Hepatitis– and Hepatoma–predisposed Rats (LEC Rats)

Marked alterations of hepatic drug–metabolizing enzymes were observed in hepatitis– and hepatoma–predisposed rats (LEC rats) fed a choline–deficient diet. The diet enhanced the development of hepatitis with severe jaundice. The levels of two major classes of cytochrome P–450, P–450(PB) and P–450(MC)...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Sugiyama, Toshihiro, Matsunaga, Mikako, Jain, Suresh K., Jain, Sadhana, Ikeda, Yoshitaka, Taniguchi, Naoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1991
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918451/
https://ncbi.nlm.nih.gov/pubmed/1904419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01861.x
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