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Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones

In order to validate whether bones' functional adaptation to mechanical loading is a local phenomenon, we randomly assigned 21 female C57BL/6 mice at 19 weeks of age to one of three equal numbered groups. All groups were treated with isoflurane anesthesia three times a week for 2 weeks (approxi...

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Bibliographic Details
Main Authors: Sugiyama, Toshihiro, Price, Joanna S., Lanyon, Lance E.
Format: Artigo
Language:Inglês
Published: Elsevier Science 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825292/
https://ncbi.nlm.nih.gov/pubmed/19733269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2009.08.054
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