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Sclerostin's role in bone's adaptive response to mechanical loading

Mechanical loading is the primary functional determinant of bone mass and architecture, and osteocytes play a key role in translating mechanical signals into (re)modelling responses. Although the precise mechanisms remain unclear, Wnt signalling pathway components, and the anti-osteogenic canonical...

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Enregistré dans:
Détails bibliographiques
Publié dans:Bone
Auteurs principaux: Galea, Gabriel L, Lanyon, Lance E, Price, Joanna S
Format: Artigo
Langue:Inglês
Publié: Elsevier Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340132/
https://ncbi.nlm.nih.gov/pubmed/27742499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.10.008
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