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Bones' Adaptive Response to Mechanical Loading Is Essentially Linear Between the Low Strains Associated With Disuse and the High Strains Associated With the Lamellar/Woven Bone Transition

There is a widely held view that the relationship between mechanical loading history and adult bone mass/strength includes an adapted state or “lazy zone” where the bone mass/strength remains constant over a wide range of strain magnitudes. Evidence to support this theory is circumstantial. We inves...

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Detalhes bibliográficos
Main Authors: Sugiyama, Toshihiro, Meakin, Lee B, Browne, William J, Galea, Gabriel L, Price, Joanna S, Lanyon, Lance E
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427886/
https://ncbi.nlm.nih.gov/pubmed/22431329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1599
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