The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells

OBJECTIVE: Drug therapy is occasionally accompanied by an idiosyncratic severe toxicity, which occurs very rarely, but can lead to patient mortality. Methazolamide, an anti-glaucomatous agent, could cause severe skin eruptions called Stevens-Johnson syndrome/toxic epidermal necrolyis (SJS/TEN). Its...

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發表在:Drug Metab Lett
Main Authors: Sasabe, Tetsuo, Maeda, Shinichiro, Kishida, Kenichi, Yamano, Mariko, Miwa, Yoshihiro, Sugiyama, Toshihiro
格式: Artigo
語言:Inglês
出版: Bentham Science Publishers 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403967/
https://ncbi.nlm.nih.gov/pubmed/28137210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1872312811666170127160931
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