Regulation of pig heart pyruvate dehydrogenase by phosphorylation. Studies on the subunit and phosphorylation stoicheiometries

по Sugden, Peter H., Randle, Philip J.
Опубликовано 1978

Stimulation of the p38 Mitogen-activated Protein Kinase Pathway in Neonatal Rat Ventricular Myocytes by the G Protein–coupled Receptor Agonists, Endothelin-1 and Phenylephrine: A R...

по Clerk, Angela, Michael, Ashour, Sugden, Peter H.
Опубликовано 1998

p90 Ribosomal S6 kinases play a significant role in early gene regulation in the cardiomyocyte response to G(q)-protein-coupled receptor stimuli, endothelin-1 and α(1)-adrenergic r...

по Amirak, Emre, Fuller, Stephen J., Sugden, Peter H., Clerk, Angela
Опубликовано 2013

ERK1/2 Signaling Dominates Over RhoA Signaling in Regulating Early Changes in RNA Expression Induced by Endothelin-1 in Neonatal Rat Cardiomyocytes

по Marshall, Andrew K., Barrett, Oliver P. T., Cullingford, Timothy E., Shanmugasundram, Achchuthan, Sugden, Peter H., Clerk, Angela
Опубликовано 2010

Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin

по Markou, Thomais, Marshall, Andrew K, Cullingford, Timothy E, Tham, El L, Sugden, Peter H, Clerk, Angela
Опубликовано 2010

Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: Effects of endothelin-1, oxidative stress and cytokines

по Cullingford, Timothy E., Butler, Matthew J., Marshall, Andrew K., Tham, El Li, Sugden, Peter H., Clerk, Angela
Опубликовано 2008

Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of...

по Clerk, Angela, Kemp, Timothy J, Harrison, Joanne G, Mullen, Anthony J, Barton, Paul J R, Sugden, Peter H
Опубликовано 2002

Regulation of Mitogen-Activated Protein Kinases in Cardiac Myocytes through the Small G Protein Rac1

по Clerk, Angela, Pham, Fong H., Fuller, Stephen J., Sahai, Erik, Aktories, Klaus, Marais, Richard, Marshall, Chris, Sugden, Peter H.
Опубликовано 2001

Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active

по Sugden, Peter H., Markou, Thomais, Fuller, Stephen J., Tham, El Li, Molkentin, Jeffery D., Paterson, Hugh F., Clerk, Angela
Опубликовано 2011

A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3)

по Fuller, Stephen J., McGuffin, Liam J., Marshall, Andrew K., Giraldo, Alejandro, Pikkarainen, Sampsa, Clerk, Angela, Sugden, Peter H.
Опубликовано 2012

Corrigendum to “Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active” [Cell Sig...

по Sugden, Peter H., Markou, Thomais, Fuller, Stephen J., Tham, El Li, Molkentin, Jeffery D., Paterson, Hugh F., Clerk, Angela
Опубликовано 2011

Feedback regulation by Atf3 in the endothelin-1-responsive transcriptome of cardiomyocytes: Egr1 is a principal Atf3 target

по Giraldo, Alejandro, Barrett, Oliver P. T., Tindall, Marcus J., Fuller, Stephen J., Amirak, Emre, Bhattacharya, Bonhi S., Sugden, Peter H., Clerk, Angela
Опубликовано 2012

The insulin receptor family and protein kinase B (Akt) are activated in the heart by alkaline pH and α(1)-adrenergic receptors

по Meijles, Daniel N., Fuller, Stephen J., Cull, Joshua J., Alharbi, Hajed O., Cooper, Susanna T.E., Sugden, Peter H., Clerk, Angela
Опубликовано в: Biochem J (2021)

Regulation of Expression of the Rat Orthologue of Mouse Double Minute 2 (MDM2) by H(2)O(2)-induced Oxidative Stress in Neonatal Rat Cardiac Myocytes

по Pikkarainen, Sampsa, Kennedy, Robert A., Marshall, Andrew K., Tham, El Li, Lay, Kenneth, Kriz, Thomas A., Handa, Balvinder S., Clerk, Angela, Sugden, Peter H.
Опубликовано 2009

The cardiomyocyte “redox rheostat”: Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death

по Meijles, Daniel N., Zoumpoulidou, Georgia, Markou, Thomais, Rostron, Kerry A., Patel, Rishi, Lay, Kenneth, Handa, Balvinder S., Wong, Bethany, Sugden, Peter H., Clerk, Angela
Опубликовано в: J Mol Cell Cardiol (2019)

MAP4K4 expression in cardiomyocytes: multiple isoforms, multiple phosphorylations and interactions with striatins

по Fuller, Stephen J., Edmunds, Nick S., McGuffin, Liam J., Hardyman, Michelle A., Cull, Joshua J., Alharbi, Hajed O., Meijles, Daniel N., Sugden, Peter H., Clerk, Angela
Опубликовано в: Biochem J (2021)

Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes

по Cullingford, Timothy E, Markou, Thomais, Fuller, Stephen J, Giraldo, Alejandro, Pikkarainen, Sampsa, Zoumpoulidou, Georgia, Alsafi, Ali, Ekere, Collins, Kemp, Timothy J, Dennis, Jayne L, Game, Laurence, Sugden, Peter H, Clerk, Angela
Опубликовано 2008

MICAL-1 Is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis

по Zhou, Yeping, Adolfs, Youri, Pijnappel, W. W. M. Pim, Fuller, Stephen J., Van der Schors, Roel C., Li, Ka Wan, Sugden, Peter H., Smit, August B., Hergovich, Alexander, Pasterkamp, R. Jeroen
Опубликовано 2011

Redox Regulation of Cardiac ASK1 (Apoptosis Signal-Regulating Kinase 1) Controls p38-MAPK (Mitogen-Activated Protein Kinase) and Orchestrates Cardiac Remodeling to Hypertension

по Meijles, Daniel N., Cull, Joshua J., Markou, Thomais, Cooper, Susanna T.E., Haines, Zoe H.R., Fuller, Stephen J., O’Gara, Peter, Sheppard, Mary N., Harding, Sian E., Sugden, Peter H., Clerk, Angela
Опубликовано в: Hypertension (2020)

The anti-cancer drug dabrafenib is not cardiotoxic and inhibits cardiac remodelling and fibrosis in a murine model of hypertension

по Meijles, Daniel N., Cull, Joshua J., Cooper, Susanna T.E., Markou, Thomais, Hardyman, Michelle A., Fuller, Stephen J., Alharbi, Hajed O., Haines, Zoe H.R., Alcantara-Alonso, Viridiana, Glennon, Peter E., Sheppard, Mary N., Sugden, Peter H., Clerk, Angela
Опубликовано в: Clin Sci (Lond) (2021)