Feedback regulation by Atf3 in the endothelin-1-responsive transcriptome of cardiomyocytes: Egr1 is a principal Atf3 target

Endothelin-1 promotes cardiomyocyte hypertrophy by inducing changes in gene expression. Immediate early genes including Atf3 (activating transcription factor 3), Egr1 (early growth response 1) and Ptgs2 (prostaglandin-endoperoxide synthase 2) are rapi-dly and transiently up-regulated by endothelin-1...

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Bibliographic Details
Main Authors: Giraldo, Alejandro, Barrett, Oliver P. T., Tindall, Marcus J., Fuller, Stephen J., Amirak, Emre, Bhattacharya, Bonhi S., Sugden, Peter H., Clerk, Angela
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365354/
https://ncbi.nlm.nih.gov/pubmed/22390138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120125
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