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MICAL-1 Is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis

MICALs (molecules interacting with CasL) are atypical multidomain flavoenzymes with diverse cellular functions. The molecular pathways employed by MICAL proteins to exert their cellular effects remain largely uncharacterized. Via an unbiased proteomics approach, we identify MICAL-1 as a binding part...

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Detalhes bibliográficos
Main Authors: Zhou, Yeping, Adolfs, Youri, Pijnappel, W. W. M. Pim, Fuller, Stephen J., Van der Schors, Roel C., Li, Ka Wan, Sugden, Peter H., Smit, August B., Hergovich, Alexander, Pasterkamp, R. Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165550/
https://ncbi.nlm.nih.gov/pubmed/21730291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01389-10
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