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Constitutively active NDR1-PIF kinase functions independent of MST1 and hMOB1 signalling
The human MST1/hMOB1/NDR1 tumour suppressor cascade regulates important cellular processes, such as centrosome duplication. hMOB1/NDR1 complex formation appears to be essential for NDR1 activation by autophosphorylation on Ser281 and hydrophobic motif (HM) phosphorylation at Thr444 by MST1. To disse...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4049220/ https://ncbi.nlm.nih.gov/pubmed/24747552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.04.011 |
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