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Regulation of DNA damage responses and cell cycle progression by hMOB2

Mps one binder proteins (MOBs) are conserved regulators of essential signalling pathways. Biochemically, human MOB2 (hMOB2) can inhibit NDR kinases by competing with hMOB1 for binding to NDRs. However, biological roles of hMOB2 have remained enigmatic. Here, we describe novel functions of hMOB2 in t...

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Vydáno v:Cell Signal
Hlavní autoři: Gomez, Valenti, Gundogdu, Ramazan, Gomez, Marta, Hoa, Lily, Panchal, Neelam, O’Driscoll, Mark, Hergovich, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276419/
https://ncbi.nlm.nih.gov/pubmed/25460043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.11.016
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