hMOB3 modulates MST1 apoptotic signaling and supports tumor growth in glioblastoma multiforme

New therapeutic targets are needed that circumvent inherent therapeutic resistance of glioblastoma multiforme (GBM). Here we report such a candidate target in the uncharacterized adaptor protein hMOB3, which we show is upregulated in GBM. In a search for its biochemical function, we found that hMOB3...

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Bibliografiske detaljer
Main Authors: Tang, Fengyuan, Zhang, Lei, Xue, Gongda, Hynx, Debby, Wang, Yuhua, Cron, Peter D., Hundsrucker, Christian, Hergovich, Alexander, Frank, Stephan, Hemmings, Brian A., Schmitz-Rohmer, Debora
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102567/
https://ncbi.nlm.nih.gov/pubmed/24872389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3430
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