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NDR Functions as a Physiological YAP1 Kinase in the Intestinal Epithelium
BACKGROUND: Phosphorylation of the transcriptional coactivator YAP1 is a key event in defining Hippo signaling outputs. Previous studies demonstrated that phosphorylation of YAP1 at serine 127 (S127) sequesters YAP1 in the cytoplasm and consequently inhibits YAP1 transcriptional activity. Mammalian...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Curr Biol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Cell Press
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4426889/ https://ncbi.nlm.nih.gov/pubmed/25601544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.11.054 |
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