NDR Functions as a Physiological YAP1 Kinase in the Intestinal Epithelium

BACKGROUND: Phosphorylation of the transcriptional coactivator YAP1 is a key event in defining Hippo signaling outputs. Previous studies demonstrated that phosphorylation of YAP1 at serine 127 (S127) sequesters YAP1 in the cytoplasm and consequently inhibits YAP1 transcriptional activity. Mammalian...

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Publicat a:Curr Biol
Autors principals: Zhang, Lei, Tang, Fengyuan, Terracciano, Luigi, Hynx, Debby, Kohler, Reto, Bichet, Sandrine, Hess, Daniel, Cron, Peter, Hemmings, Brian A., Hergovich, Alexander, Schmitz-Rohmer, Debora
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426889/
https://ncbi.nlm.nih.gov/pubmed/25601544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.11.054
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