NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development

Studies of mammalian tissue culture cells indicate that the conserved and distinct NDR isoforms, NDR1 and NDR2, play essential cell biological roles. However, mice lacking either Ndr1 or Ndr2 alone develop normally. Here, we studied the physiological consequences of inactivating both NDR1 and NDR2 i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schmitz-Rohmer, Debora, Probst, Simone, Yang, Zhong-Zhou, Laurent, Frédéric, Stadler, Michael B., Zuniga, Aimée, Zeller, Rolf, Hynx, Debby, Hemmings, Brian A., Hergovich, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549247/
https://ncbi.nlm.nih.gov/pubmed/26305214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136566
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