Small Heat Shock Proteins Protect Against α-Synuclein-Induced Toxicity and Aggregation

Por Outeiro, Tiago Fleming, Klucken, Jochen, Strathearn, Katherine E., Liu, Fang, Nguyen, Paul, Rochet, Jean-Christophe, Hyman, Bradley T., McLean, Pamela J.
Publicado em 2006

Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study

Por Dumitriu, Alexandra, Pacheco, Chris D., Wilk, Jemma B., Strathearn, Katherine E., Latourelle, Jeanne C., Goldwurm, Stefano, Pezzoli, Gianni, Rochet, Jean-Christophe, Lindquist, Susan, Myers, Richard H.
Publicado em 2011

α–Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

Por Gitler, Aaron D., Chesi, Alessandra, Geddie, Melissa L., Strathearn, Katherine E., Hamamichi, Shusei, Hill, Kathryn J., Caldwell, Kim A., Caldwell, Guy A., Cooper, Antony A., Rochet, Jean-Christophe, Lindquist, Susan
Publicado em 2009

Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson’s disease

Por Strathearn, Katherine E., Yousef, Gad G., Grace, Mary H., Roy, Susan L., Tambe, Mitali A., Ferruzzi, Mario G., Wu, Qing-Li, Simon, James E., Lila, Mary Ann, Rochet, Jean-Christophe
Publicado em 2014

The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis

Por Gitler, Aaron D., Bevis, Brooke J., Shorter, James, Strathearn, Katherine E., Hamamichi, Shusei, Su, Linhui Julie, Caldwell, Kim A., Caldwell, Guy A., Rochet, Jean-Christophe, McCaffery, J. Michael, Barlowe, Charles, Lindquist, Susan
Publicado em 2008

α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson’s Models

Por Cooper, Antony A., Gitler, Aaron D., Cashikar, Anil, Haynes, Cole M., Hill, Kathryn J., Bhullar, Bhupinder, Liu, Kangning, Xu, Kexiang, Strathearn, Katherine E., Liu, Fang, Cao, Songsong, Caldwell, Kim A., Caldwell, Guy A., Marsischky, Gerald, Kolodner, Richard D., LaBaer, Joshua, Rochet, Jean-Christophe, Bonini, Nancy M., Lindquist, Susan
Publicado em 2006

Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models

Por Su, Linhui Julie, Auluck, Pavan K., Outeiro, Tiago Fleming, Yeger-Lotem, Esti, Kritzer, Joshua A., Tardiff, Daniel F., Strathearn, Katherine E., Liu, Fang, Cao, Songsong, Hamamichi, Shusei, Hill, Kathryn J., Caldwell, Kim A., Bell, George W., Fraenkel, Ernest, Cooper, Antony A., Caldwell, Guy A., McCaffery, J. Michael, Rochet, Jean-Christophe, Lindquist, Susan
Publicado em 2010