Small Heat Shock Proteins Protect Against α-Synuclein-Induced Toxicity and Aggregation

Protein misfolding and inclusion formation are common events in neurodegenerative diseases, such as Parkinson’s disease (PD), Alzheimer’s disease (AD) or Huntington’s disease (HD). Alpha-synuclein (aSyn) is the main protein component of inclusions called Lewy bodies (LB) which are pathognomic of PD,...

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Autors principals: Outeiro, Tiago Fleming, Klucken, Jochen, Strathearn, Katherine E., Liu, Fang, Nguyen, Paul, Rochet, Jean-Christophe, Hyman, Bradley T., McLean, Pamela J.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934426/
https://ncbi.nlm.nih.gov/pubmed/17081499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.10.085
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