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Targeting heat shock proteins to modulate α-synuclein toxicity

Parkinson’s disease is a slowly progressive neurodegenerative disorder typically characterized by the loss of dopaminergic neurons within the substantia nigra pars compacta, and the intraneuronal deposition of insoluble protein aggregates chiefly comprised of α-synuclein. Patients experience debilit...

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Detalhes bibliográficos
Main Authors: Jones, Daryl Rhys, Moussaud, Simon, McLean, Pamela
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886379/
https://ncbi.nlm.nih.gov/pubmed/24409201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756285613493469
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