Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study

Although family history is a well-established risk factor for Parkinson's disease (PD), fewer than 5% of PD cases can be attributed to known genetic mutations. The etiology for the remainder of PD cases is unclear; however, neuronal accumulation of the protein α-synuclein is common to nearly al...

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Autors principals: Dumitriu, Alexandra, Pacheco, Chris D., Wilk, Jemma B., Strathearn, Katherine E., Latourelle, Jeanne C., Goldwurm, Stefano, Pezzoli, Gianni, Rochet, Jean-Christophe, Lindquist, Susan, Myers, Richard H.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063983/
https://ncbi.nlm.nih.gov/pubmed/21258085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr026
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