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Haplotypes and gene expression implicate the MAPT region for Parkinson disease: The GenePD Study

BACKGROUND: Microtubule-associated protein tau (MAPT) has been associated with several neurodegenerative disorders including forms of parkinsonism and Parkinson disease (PD). We evaluated the association of the MAPT region with PD in a large cohort of familial PD cases recruited by the GenePD Study....

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Autors principals: Tobin, J.E., Latourelle, J.C., Lew, M.F., Klein, C., Suchowersky, O., Shill, H.A., Golbe, L.I., Mark, M.H., Growdon, J.H., Wooten, G.F., Racette, B.A., Perlmutter, J.S., Watts, R., Guttman, M., Baker, K.B., Goldwurm, S., Pezzoli, G., Singer, C., Saint-Hilaire, M.H., Hendricks, A.E., Williamson, S., Nagle, M.W., Wilk, J.B., Massood, T., Laramie, J.M., DeStefano, A.L., Litvan, I., Nicholson, G., Corbett, A., Isaacson, S., Burn, D.J., Chinnery, P.F., Pramstaller, P.P., Sherman, S., Al-hinti, J., Drasby, E., Nance, M., Moller, A.T., Ostergaard, K., Roxburgh, R., Snow, B., Slevin, J.T., Cambi, F., Gusella, J.F., Myers, R.H.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654275/
https://ncbi.nlm.nih.gov/pubmed/18509094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.wnl.0000304051.01650.23
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