Hypoxia and oxidative stress in breast cancer: Tumour hypoxia – therapeutic considerations

Tekijä Williams, Kaye J, Cowen, Rachel L, Stratford, Ian J
Julkaistu 2001

Comparison of Doxycycline Delivery Methods for Tet-Inducible Gene Expression in a Subcutaneous Xenograft Model

Tekijä Cawthorne, Christopher, Swindell, Ric, Stratford, Ian J., Dive, Caroline, Welman, Arkadiusz
Julkaistu 2007

Dissecting the role of multiple reductases in bioactivation and cytotoxicity of the antitumor agent RH1

Tekijä Yan, Chao, Kepa, Jadwiga K., Siegel, David, Stratford, Ian J., Ross, David
Julkaistu 2008

Radiation enhances the therapeutic effect of Banoxantrone in hypoxic tumour cells with elevated levels of nitric oxide synthase

Tekijä MEHIBEL, MANAL, SINGH, SIMENDRA, COWEN, RACHEL L., WILLIAMS, KAYE J., STRATFORD, IAN J.
Julkaisussa Oncol Rep (2016)

PCAF is a HIF-1α cofactor that regulates p53 transcriptional activity in hypoxia

Tekijä Xenaki, Georgia, Ontikatze, Teona, Rajendran, Ramkumar, Stratford, Ian J., Dive, Caroline, Krstic-Demonacos, Marija, Demonacos, Constantinos
Julkaistu 2008

In silico screening reveals structurally diverse, nanomolar inhibitors of NQO2 that are functionally active in cells and can modulate NFκB signalling

Tekijä Nolan, Karen A., Dunstan, Mark S., Caraher, Mary C., Scott, Katherine A., Leys, David, Stratford, Ian J.
Julkaistu 2011

Site and Strain-Specific Variation in Gut Microbiota Profiles and Metabolism in Experimental Mice

Tekijä Friswell, Melissa K., Gika, Helen, Stratford, Ian J., Theodoridis, Georgios, Telfer, Brian, Wilson, Ian D., McBain, Andrew J.
Julkaistu 2010

The two common polymorphic forms of human NRH-quinone oxidoreductase 2 (NQO2) have different biochemical properties

Tekijä Megarity, Clare F., Gill, James R.E., Clare Caraher, M., Stratford, Ian J., Nolan, Karen A., Timson, David J.
Julkaistu 2014

Akt inhibition improves long‐term tumour control following radiotherapy by altering the microenvironment

Tekijä Searle, Emma J, Telfer, Brian A, Mukherjee, Debayan, Forster, Duncan M, Davies, Barry R, Williams, Kaye J, Stratford, Ian J, Illidge, Tim M
Julkaisussa EMBO Mol Med (2017)

Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and -Independent Mechanisms and Contributes to Drug Resistance

Tekijä Erler, Janine T., Cawthorne, Christopher J., Williams, Kaye J., Koritzinsky, Marianne, Wouters, Bradley G., Wilson, Clare, Miller, Crispin, Demonacos, Costas, Stratford, Ian J., Dive, Caroline
Julkaistu 2004

Glucocorticoid receptor over-expression promotes human small cell lung cancer apoptosis in vivo and thereby slows tumor growth

Tekijä Sommer, Paula, Cowen, Rachel L, Berry, Andrew, Cookson, Ann, Telfer, Brian A, Williams, Kaye J, Stratford, Ian J, Kay, Paul, White, Anne, Ray, David W
Julkaistu 2010

Inhibition of poly(ADP-ribose) polymerase-1 by olaparib (AZD2281) increases the radiosensitivity of a lung tumor xenograft

Tekijä Senra, Joana M., Telfer, Brian A., Cherry, Kim E., McCrudden, Cian M., Hirst, David G., O’Connor, Mark J., Wedge, Stephen R., Stratford, Ian J.
Julkaistu 2011

Inhibition of Monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport

Tekijä Bola, Becky M., Chadwick, Amy L., Michopoulos, Filippos, Blount, Kathryn G., Telfer, Brian A., Williams, Kaye J., Smith, Paul D, Critchlow, Susan E., Stratford, Ian J.
Julkaisussa Mol Cancer Ther (2014)

Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin

Tekijä Sivalingam, Vanitha N., Latif, Ayşe, Kitson, Sarah, McVey, Rhona, Finegan, Katherine G., Marshall, Kay, Lisanti, Michael P., Sotgia, Federica, Stratford, Ian J., Crosbie, Emma J.
Julkaisussa Br J Cancer (2019)

Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters

Tekijä Mehibel, Manal, Ortiz-Martinez, Fernando, Voelxen, Nadine, Boyers, Amy, Chadwick, Amy, Telfer, Brian A., Mueller-Klieser, Wolfgang, West, Catharine M., Critchlow, Susan E., Williams, Kaye J., Stratford, Ian J.
Julkaisussa Sci Rep (2018)

A novel systemically administered toll-like receptor 7 agonist potentiates the effect of ionizing radiation in murine solid tumor models

Tekijä Adlard, Amy L, Dovedi, Simon J, Telfer, Brian A, Koga-Yamakawa, Erina, Pollard, Charlotte, Honeychurch, Jamie, Illidge, Timothy M, Murata, Masashi, Robinson, David T, Jewsbury, Philip J, Wilkinson, Robert W, Stratford, Ian J
Julkaisussa Int J Cancer (2014)

Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell–mediated immunotherapy

Tekijä Silk, Jonathan D., Hermans, Ian F., Gileadi, Uzi, Chong, Tsung Wen, Shepherd, Dawn, Salio, Mariolina, Mathew, Bini, Schmidt, Richard R., Lunt, Sarah Jane, Williams, Kaye J., Stratford, Ian J., Harris, Adrian L., Cerundolo, Vincenzo
Julkaistu 2004

Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancer

Tekijä Latif, Ayşe, Chadwick, Amy L., Kitson, Sarah J., Gregson, Hannah J., Sivalingam, Vanitha N., Bolton, James, McVey, Rhona J., Roberts, Stephen A., Marshall, Kay M., Williams, Kaye J., Stratford, Ian J., Crosbie, Emma J.
Julkaisussa BMC Clin Pathol (2017)

Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination...

Tekijä Dovedi, Simon J., Adlard, Amy L., Ota, Yosuke, Murata, Masashi, Sugaru, Eiji, Koga-Yamakawa, Erina, Eguchi, Ken, Hirose, Yuko, Yamamoto, Setsuko, Umehara, Hiroki, Honeychurch, Jamie, Cheadle, Eleanor J., Hughes, Gareth, Jewsbury, Philip J., Wilkinson, Robert W., Stratford, Ian J., Illidge, Timothy M.
Julkaisussa Oncotarget (2016)

Expression of NAD(P)H quinone dehydrogenase 1 (NQO1) is increased in the endometrium of women with endometrial cancer and women with polycystic ovary syndrome

Tekijä Atiomo, William, Shafiee, Mohamad Nasir, Chapman, Caroline, Metzler, Veronika M., Abouzeid, Jad, Latif, Ayşe, Chadwick, Amy, Kitson, Sarah, Sivalingam, Vanitha N., Stratford, Ian J., Rutland, Catrin S., Persson, Jenny L., Ødum, Niels, Fuentes‐Utrilla, Pablo, Jeyapalan, Jennie N., Heery, David M., Crosbie, Emma J., Mongan, Nigel P.
Julkaisussa Clin Endocrinol (Oxf) (2017)