Distinct patterns of infiltrating CD8+ T cells in HPV+ and CD68 macrophages in HPV- oropharyngeal squamous cell carcinomas are associated with better clinical outcome but PD-L1 exp...

অনুযায়ী Oguejiofor, Kenneth, Galletta-Williams, Henry, Dovedi, Simon J., Roberts, Darren L., Stern, Peter L., West, Catharine M.L.
প্রকাশিত Oncotarget (2017)

Radiation and PD-(L)1 treatment combinations: immune response and dose optimization via a predictive systems model

অনুযায়ী Kosinsky, Yuri, Dovedi, Simon J., Peskov, Kirill, Voronova, Veronika, Chu, Lulu, Tomkinson, Helen, Al-Huniti, Nidal, Stanski, Donald R., Helmlinger, Gabriel
প্রকাশিত J Immunother Cancer (2018)

Antitumor efficacy of radiation plus immunotherapy depends upon dendritic cell activation of effector CDS(+) T cells

অনুযায়ী Dovedi, Simon J., Lipowska-Bhalla, Grazyna, Beers, Stephen A., Cheadle, Eleanor J., Mu, Lijun, Glennie, Martin J., Illidge, Timothy M., Honeychurch, Jamie
প্রকাশিত Cancer Immunol Res (2016)

A cell-engineered system to assess tumor cell sensitivity to CD8(+) T cell-mediated cytotoxicity

অনুযায়ী Nelson, Nadine, Lopez-Pelaez, Marta, Palazon, Asis, Poon, Edmund, De La Roche, Maike, Barry, Simon, Valge-Archer, Viia, Wilkinson, Robert W., Dovedi, Simon J., Smith, Paul D.
প্রকাশিত Oncoimmunology (2019)

A LAT-Based Signaling Complex in the Immunological Synapse as Determined with Live Cell Imaging Is Less Stable in T Cells with Regulatory Capability

অনুযায়ী Li, Yikui, Tunbridge, Helen M., Britton, Graham J., Hill, Elaine V., Sinai, Parisa, Cirillo, Silvia, Thompson, Clare, Fallah-Arani, Farnaz, Dovedi, Simon J., Wraith, David C., Wülfing, Christoph
প্রকাশিত Cells (2021)

A novel systemically administered toll-like receptor 7 agonist potentiates the effect of ionizing radiation in murine solid tumor models

অনুযায়ী Adlard, Amy L, Dovedi, Simon J, Telfer, Brian A, Koga-Yamakawa, Erina, Pollard, Charlotte, Honeychurch, Jamie, Illidge, Timothy M, Murata, Masashi, Robinson, David T, Jewsbury, Philip J, Wilkinson, Robert W, Stratford, Ian J
প্রকাশিত Int J Cancer (2014)

Novel non-terminal tumor sampling procedure using fine needle aspiration supports immuno-oncology biomarker discovery in preclinical mouse models

অনুযায়ী Sitnikova, Suzanne Isabelle, Munnings-Tomes, Sophie, Galvani, Elena, Kentner, Stacy, Mulgrew, Kathy, Rands, Chris, España Agustí, Judit, Zhang, Tianhui, Ilieva, Kristina M, Rosignoli, Guglielmo, Ghadially, Hormas, Robinson, Matthew J, Slidel, Tim, Wilkinson, Robert W, Dovedi, Simon J
প্রকাশিত J Immunother Cancer (2021)

The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment

অনুযায়ী Poon, Edmund, Mullins, Stefanie, Watkins, Amanda, Williams, Geoffrey S., Koopmann, Jens-Oliver, Di Genova, Gianfranco, Cumberbatch, Marie, Veldman-Jones, Margaret, Grosskurth, Shaun E., Sah, Vasu, Schuller, Alwin, Reimer, Corrine, Dovedi, Simon J., Smith, Paul D., Stewart, Ross, Wilkinson, Robert W.
প্রকাশিত J Immunother Cancer (2017)

Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination...

অনুযায়ী Dovedi, Simon J., Adlard, Amy L., Ota, Yosuke, Murata, Masashi, Sugaru, Eiji, Koga-Yamakawa, Erina, Eguchi, Ken, Hirose, Yuko, Yamamoto, Setsuko, Umehara, Hiroki, Honeychurch, Jamie, Cheadle, Eleanor J., Hughes, Gareth, Jewsbury, Philip J., Wilkinson, Robert W., Stratford, Ian J., Illidge, Timothy M.
প্রকাশিত Oncotarget (2016)

PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and target tumor cells within the tumor

অনুযায়ী Ambler, Rachel, Edmunds, Grace L., Tan, Sin Lih, Cirillo, Silvia, Pernes, Jane I., Ruan, Xiongtao, Huete-Carrasco, Jorge, Wong, Carissa C. W., Lu, Jiahe, Ward, Juma, Toti, Giulia, Hedges, Alan J., Dovedi, Simon J., Murphy, Robert F., Morgan, David J., Wülfing, Christoph
প্রকাশিত Sci Signal (2020)

Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies

অনুযায়ী Mullins, Stefanie R., Vasilakos, John P., Deschler, Katharina, Grigsby, Iwen, Gillis, Pete, John, Julius, Elder, Matthew J., Swales, John, Timosenko, Elina, Cooper, Zachary, Dovedi, Simon J., Leishman, Andrew J., Luheshi, Nadia, Elvecrog, James, Tilahun, Ashenafi, Goodwin, Richard, Herbst, Ronald, Tomai, Mark A., Wilkinson, Robert W.
প্রকাশিত J Immunother Cancer (2019)