Radiogenomics: a systems biology approach to understanding genetic risk factors for radiotherapy toxicity ?

Por Herskind, Carsten, Talbot, Christopher J., Kerns, Sarah L., Veldwijk, Marlon R., Rosenstein, Barry S., West, Catharine M. L.
Publicado no Cancer Lett (2016)

Distinct patterns of infiltrating CD8+ T cells in HPV+ and CD68 macrophages in HPV- oropharyngeal squamous cell carcinomas are associated with better clinical outcome but PD-L1 exp...

Por Oguejiofor, Kenneth, Galletta-Williams, Henry, Dovedi, Simon J., Roberts, Darren L., Stern, Peter L., West, Catharine M.L.
Publicado no Oncotarget (2017)

Exon Array Analysis of Head and Neck Cancers Identifies a Hypoxia Related Splice Variant of LAMA3 Associated with a Poor Prognosis

Por Moller-Levet, Carla S., Betts, Guy N. J., Harris, Adrian L., Homer, Jarrod J., West, Catharine M. L., Miller, Crispin J.
Publicado em 2009

No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: Results from the RAPPER study

Por Barnett, Gillian C., Coles, Charlotte E., Burnet, Neil G., Pharoah, Paul D.P., Wilkinson, Jennifer, West, Catharine M.L., Elliott, Rebecca M., Baynes, Caroline, Dunning, Alison M.
Publicado em 2010

Investigation of Radiosensitivity Gene Signatures in Cancer Cell Lines

Por Hall, John S., Iype, Rohan, Senra, Joana, Taylor, Janet, Armenoult, Lucile, Oguejiofor, Kenneth, Li, Yaoyong, Stratford, Ian, Stern, Peter L., O’Connor, Mark J., Miller, Crispin J., West, Catharine M. L.
Publicado em 2014

Necrosis predicts benefit from hypoxia-modifying therapy in patients with high risk bladder cancer enrolled in a phase III randomised trial()

Por Eustace, Amanda, Irlam, Joely J., Taylor, Janet, Denley, Helen, Agrawal, Shailesh, Choudhury, Ananya, Ryder, David, Ord, Jonathan J., Harris, Adrian L., Rojas, Ana M., Hoskin, Peter J., West, Catharine M.L.
Publicado em 2013

STROGAR – STrengthening the Reporting Of Genetic Association studies in Radiogenomics

Por Kerns, Sarah L., de Ruysscher, Dirk, Andreassen, Christian N., Azria, David, Barnett, Gillian C., Chang-Claude, Jenny, Davidson, Susan, Deasy, Joseph O., Dunning, Alison M., Ostrer, Harry, Rosenstein, Barry S., West, Catharine M.L., Bentzen, Søren M.
Publicado no Radiother Oncol (2013)

Cediranib combined with carboplatin and paclitaxel in patients with metastatic or recurrent cervical cancer (CIRCCa): a randomised, double-blind, placebo-controlled phase 2 trial

Por Symonds, R Paul, Gourley, Charlie, Davidson, Susan, Carty, Karen, McCartney, Elaine, Rai, Debbie, Banerjee, Susana, Jackson, David, Lord, Rosemary, McCormack, Mary, Hudson, Emma, Reed, Nicholas, Flubacher, Maxine, Jankowska, Petra, Powell, Melanie, Dive, Caroline, West, Catharine M L, Paul, James
Publicado no Lancet Oncol (2015)

Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity

Por Ahmed, Mahbubl, Dorling, Leila, Kerns, Sarah, Fachal, Laura, Elliott, Rebecca, Partliament, Matt, Rosenstein, Barry S, Vega, Ana, Gómez-Caamaño, Antonio, Barnett, Gill, Dearnaley, David P, Hall, Emma, Sydes, Matt, Burnet, Neil, Pharoah, Paul D P, Eeles, Ros, West, Catharine M L
Publicado no Br J Cancer (2016)

Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity

Por Barnett, Gillian C., Elliott, Rebecca M., Alsner, Jan, Andreassen, Christian N., Abdelhay, Osama, Burnet, Neil G., Chang-Claude, Jenny, Coles, Charlotte E., Gutiérrez-Enríquez, Sara, Fuentes-Raspall, Maria J., Alonso-Muñoz, Maria C., Kerns, Sarah, Raabe, Annette, Symonds, R. Paul, Seibold, Petra, Talbot, Chris J., Wenz, Frederik, Wilkinson, Jennifer, Yarnold, John, Dunning, Alison M., Rosenstein, Barry S., West, Catharine M.L., Bentzen, Søren M.
Publicado em 2012

Epigenetic downregulation of human disabled homolog 2 switches TGF-β from a tumor suppressor to a tumor promoter

Por Hannigan, Adèle, Smith, Paul, Kalna, Gabriela, Lo Nigro, Cristiana, Orange, Clare, O’Brien, Darren I., Shah, Reshma, Syed, Nelofer, Spender, Lindsay C., Herrera, Blanca, Thurlow, Johanna K., Lattanzio, Laura, Monteverde, Martino, Maurer, Meghan E., Buffa, Francesca M., Mann, Jelena, Chu, David C.K., West, Catharine M.L., Patridge, Max, Oien, Karin A., Cooper, Jonathan A., Frame, Margaret C., Harris, Adrian L., Hiller, Louise, Nicholson, Linda J., Gasco, Milena, Crook, Tim, Inman, Gareth J.
Publicado em 2010

Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer

Por Kerns, Sarah L., Dorling, Leila, Fachal, Laura, Bentzen, Søren, Pharoah, Paul D.P., Barnes, Daniel R., Gómez-Caamaño, Antonio, Carballo, Ana M., Dearnaley, David P., Peleteiro, Paula, Gulliford, Sarah L., Hall, Emma, Michailidou, Kyriaki, Carracedo, Ángel, Sia, Michael, Stock, Richard, Stone, Nelson N., Sydes, Matthew R., Tyrer, Jonathan P., Ahmed, Shahana, Parliament, Matthew, Ostrer, Harry, Rosenstein, Barry S., Vega, Ana, Burnet, Neil G., Dunning, Alison M., Barnett, Gillian C., West, Catharine M.L.
Publicado no EBioMedicine (2016)