No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: Results from the RAPPER study

BACKGROUND AND PURPOSE: Several small studies have reported associations between TGFB1 single nucleotide polymorphisms (SNPs), considered to increase secretion of TGF-β1, and greater than 3-fold increases in incidence of fibrosis – an indicator of late toxicity after radiotherapy in breast cancer pa...

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Bibliografische gegevens
Hoofdauteurs: Barnett, Gillian C., Coles, Charlotte E., Burnet, Neil G., Pharoah, Paul D.P., Wilkinson, Jennifer, West, Catharine M.L., Elliott, Rebecca M., Baynes, Caroline, Dunning, Alison M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120654/
https://ncbi.nlm.nih.gov/pubmed/20096948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2009.12.006
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