Patients with a high polygenic risk of breast cancer do not have an increased risk of radiotherapy toxicity

PURPOSE: It has been hypothesized that increased predisposition to breast cancer may correlate with radiosensitivity and thus increased risk of toxicity following breast irradiation. This study investigated the relationship between common breast cancer risk variants and radiotherapy toxicity. EXPERI...

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Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Dorling, Leila, Barnett, Gillian C., Michailidou, Kyriaki, Coles, Charlotte E., Burnet, Neil G., Yarnold, John, Elliott, Rebecca M., Dunning, Alison M., Pharoah, Paul D. P., West, Catharine M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751620/
https://ncbi.nlm.nih.gov/pubmed/26510858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1080
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