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Patients with a high polygenic risk of breast cancer do not have an increased risk of radiotherapy toxicity

PURPOSE: It has been hypothesized that increased predisposition to breast cancer may correlate with radiosensitivity and thus increased risk of toxicity following breast irradiation. This study investigated the relationship between common breast cancer risk variants and radiotherapy toxicity. EXPERI...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Dorling, Leila, Barnett, Gillian C., Michailidou, Kyriaki, Coles, Charlotte E., Burnet, Neil G., Yarnold, John, Elliott, Rebecca M., Dunning, Alison M., Pharoah, Paul D. P., West, Catharine M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751620/
https://ncbi.nlm.nih.gov/pubmed/26510858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1080
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