Understanding the influence of the tumor microenvironment on macrophage responses to CD40 agonists

Por Luheshi, Nadia, Davies, Gareth, Legg, James
Publicado em 2014

The Dynamics and Mechanisms of Interleukin-1α and β Nuclear Import

Por Luheshi, Nadia M, Rothwell, Nancy J, Brough, David
Publicado em 2008

Nuclear retention of interleukin-1α by necrotic cells: a mechanism to dampen sterile inflammation

Por Luheshi, Nadia M., McColl, Barry W., Brough, David
Publicado em 2009

Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages

Por Luheshi, Nadia M, Giles, James A, Lopez-Castejon, Gloria, Brough, David
Publicado em 2012

Interleukin-1α expression precedes IL-1β after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues

Por Luheshi, Nadia M, Kovács, Krisztina J, Lopez-Castejon, Gloria, Brough, David, Denes, Adam
Publicado em 2011

Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding

Por Borrok, M Jack, Luheshi, Nadia M, Beyaz, Nurten, Davies, Gareth C, Legg, James W, Wu, Herren, Dall'Acqua, William F, Tsui, Ping
Publicado no MAbs (2015)

Deubiquitinases Regulate the Activity of Caspase-1 and Interleukin-1β Secretion via Assembly of the Inflammasome

Por Lopez-Castejon, Gloria, Luheshi, Nadia M., Compan, Vincent, High, Stephen, Whitehead, Roger C., Flitsch, Sabine, Kirov, Aleksandr, Prudovsky, Igor, Swanton, Eileithyia, Brough, David
Publicado em 2013

Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model

Por Luheshi, Nadia M., Coates-Ulrichsen, Jane, Harper, James, Mullins, Stefanie, Sulikowski, Michal G., Martin, Philip, Brown, Lee, Lewis, Arthur, Davies, Gareth, Morrow, Michelle, Wilkinson, Robert W.
Publicado no Oncotarget (2016)

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition

Por Young, Helen L., Rowling, Emily J., Bugatti, Mattia, Giurisato, Emanuele, Luheshi, Nadia, Arozarena, Imanol, Acosta, Juan-Carlos, Kamarashev, Jivko, Frederick, Dennie T., Cooper, Zachary A., Reuben, Alexandre, Gil, Jesus, Flaherty, Keith T., Wargo, Jennifer A., Vermi, William, Smith, Michael P., Wellbrock, Claudia, Hurlstone, Adam
Publicado no J Exp Med (2017)

Boron-Based Inhibitors of the NLRP3 Inflammasome

Por Baldwin, Alex G., Rivers-Auty, Jack, Daniels, Michael J.D., White, Claire S., Schwalbe, Carl H., Schilling, Tom, Hammadi, Halah, Jaiyong, Panichakorn, Spencer, Nicholas G., England, Hazel, Luheshi, Nadia M., Kadirvel, Manikandan, Lawrence, Catherine B., Rothwell, Nancy J., Harte, Michael K., Bryce, Richard A., Allan, Stuart M., Eder, Claudia, Freeman, Sally, Brough, David
Publicado no Cell Chem Biol (2017)