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Interleukin-1α expression precedes IL-1β after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues

BACKGROUND: Cerebral ischemia is a devastating condition in which the outcome is heavily influenced by inflammatory processes, which can augment primary injury caused by reduced blood supply. The cytokines interleukin-1α (IL-1α) and IL-1β are key contributors to ischemic brain injury. However, there...

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Detalhes bibliográficos
Main Authors: Luheshi, Nadia M, Kovács, Krisztina J, Lopez-Castejon, Gloria, Brough, David, Denes, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259068/
https://ncbi.nlm.nih.gov/pubmed/22206506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-186
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