Boron-Based Inhibitors of the NLRP3 Inflammasome

NLRP3 is a receptor important for host responses to infection, yet is also known to contribute to devastating diseases such as Alzheimer's disease, diabetes, atherosclerosis, and others, making inhibitors for NLRP3 sought after. One of the inhibitors currently in use is 2-aminoethoxy diphenylbo...

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Gepubliceerd in:Cell Chem Biol
Hoofdauteurs: Baldwin, Alex G., Rivers-Auty, Jack, Daniels, Michael J.D., White, Claire S., Schwalbe, Carl H., Schilling, Tom, Hammadi, Halah, Jaiyong, Panichakorn, Spencer, Nicholas G., England, Hazel, Luheshi, Nadia M., Kadirvel, Manikandan, Lawrence, Catherine B., Rothwell, Nancy J., Harte, Michael K., Bryce, Richard A., Allan, Stuart M., Eder, Claudia, Freeman, Sally, Brough, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696570/
https://ncbi.nlm.nih.gov/pubmed/28943355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.08.011
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