Boron-Based Inhibitors of the NLRP3 Inflammasome

NLRP3 is a receptor important for host responses to infection, yet is also known to contribute to devastating diseases such as Alzheimer's disease, diabetes, atherosclerosis, and others, making inhibitors for NLRP3 sought after. One of the inhibitors currently in use is 2-aminoethoxy diphenylbo...

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Bibliographic Details
Published in:Cell Chem Biol
Main Authors: Baldwin, Alex G., Rivers-Auty, Jack, Daniels, Michael J.D., White, Claire S., Schwalbe, Carl H., Schilling, Tom, Hammadi, Halah, Jaiyong, Panichakorn, Spencer, Nicholas G., England, Hazel, Luheshi, Nadia M., Kadirvel, Manikandan, Lawrence, Catherine B., Rothwell, Nancy J., Harte, Michael K., Bryce, Richard A., Allan, Stuart M., Eder, Claudia, Freeman, Sally, Brough, David
Format: Artigo
Language:Inglês
Published: Cell Press 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696570/
https://ncbi.nlm.nih.gov/pubmed/28943355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.08.011
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