Hypoxia and oxidative stress in breast cancer: Tumour hypoxia – therapeutic considerations

ανά Williams, Kaye J, Cowen, Rachel L, Stratford, Ian J
Έκδοση 2001

Comparison of Doxycycline Delivery Methods for Tet-Inducible Gene Expression in a Subcutaneous Xenograft Model

ανά Cawthorne, Christopher, Swindell, Ric, Stratford, Ian J., Dive, Caroline, Welman, Arkadiusz
Έκδοση 2007

Dissecting the role of multiple reductases in bioactivation and cytotoxicity of the antitumor agent RH1

ανά Yan, Chao, Kepa, Jadwiga K., Siegel, David, Stratford, Ian J., Ross, David
Έκδοση 2008

Radiation enhances the therapeutic effect of Banoxantrone in hypoxic tumour cells with elevated levels of nitric oxide synthase

ανά MEHIBEL, MANAL, SINGH, SIMENDRA, COWEN, RACHEL L., WILLIAMS, KAYE J., STRATFORD, IAN J.
Τόπος έκδοσης Oncol Rep (2016)

PCAF is a HIF-1α cofactor that regulates p53 transcriptional activity in hypoxia

ανά Xenaki, Georgia, Ontikatze, Teona, Rajendran, Ramkumar, Stratford, Ian J., Dive, Caroline, Krstic-Demonacos, Marija, Demonacos, Constantinos
Έκδοση 2008

In silico screening reveals structurally diverse, nanomolar inhibitors of NQO2 that are functionally active in cells and can modulate NFκB signalling

ανά Nolan, Karen A., Dunstan, Mark S., Caraher, Mary C., Scott, Katherine A., Leys, David, Stratford, Ian J.
Έκδοση 2011

Site and Strain-Specific Variation in Gut Microbiota Profiles and Metabolism in Experimental Mice

ανά Friswell, Melissa K., Gika, Helen, Stratford, Ian J., Theodoridis, Georgios, Telfer, Brian, Wilson, Ian D., McBain, Andrew J.
Έκδοση 2010

The two common polymorphic forms of human NRH-quinone oxidoreductase 2 (NQO2) have different biochemical properties

ανά Megarity, Clare F., Gill, James R.E., Clare Caraher, M., Stratford, Ian J., Nolan, Karen A., Timson, David J.
Έκδοση 2014

Akt inhibition improves long‐term tumour control following radiotherapy by altering the microenvironment

ανά Searle, Emma J, Telfer, Brian A, Mukherjee, Debayan, Forster, Duncan M, Davies, Barry R, Williams, Kaye J, Stratford, Ian J, Illidge, Tim M
Τόπος έκδοσης EMBO Mol Med (2017)

Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and -Independent Mechanisms and Contributes to Drug Resistance

ανά Erler, Janine T., Cawthorne, Christopher J., Williams, Kaye J., Koritzinsky, Marianne, Wouters, Bradley G., Wilson, Clare, Miller, Crispin, Demonacos, Costas, Stratford, Ian J., Dive, Caroline
Έκδοση 2004

Glucocorticoid receptor over-expression promotes human small cell lung cancer apoptosis in vivo and thereby slows tumor growth

ανά Sommer, Paula, Cowen, Rachel L, Berry, Andrew, Cookson, Ann, Telfer, Brian A, Williams, Kaye J, Stratford, Ian J, Kay, Paul, White, Anne, Ray, David W
Έκδοση 2010

Inhibition of poly(ADP-ribose) polymerase-1 by olaparib (AZD2281) increases the radiosensitivity of a lung tumor xenograft

ανά Senra, Joana M., Telfer, Brian A., Cherry, Kim E., McCrudden, Cian M., Hirst, David G., O’Connor, Mark J., Wedge, Stephen R., Stratford, Ian J.
Έκδοση 2011

Inhibition of Monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport

ανά Bola, Becky M., Chadwick, Amy L., Michopoulos, Filippos, Blount, Kathryn G., Telfer, Brian A., Williams, Kaye J., Smith, Paul D, Critchlow, Susan E., Stratford, Ian J.
Τόπος έκδοσης Mol Cancer Ther (2014)

Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin

ανά Sivalingam, Vanitha N., Latif, Ayşe, Kitson, Sarah, McVey, Rhona, Finegan, Katherine G., Marshall, Kay, Lisanti, Michael P., Sotgia, Federica, Stratford, Ian J., Crosbie, Emma J.
Τόπος έκδοσης Br J Cancer (2019)

Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters

ανά Mehibel, Manal, Ortiz-Martinez, Fernando, Voelxen, Nadine, Boyers, Amy, Chadwick, Amy, Telfer, Brian A., Mueller-Klieser, Wolfgang, West, Catharine M., Critchlow, Susan E., Williams, Kaye J., Stratford, Ian J.
Τόπος έκδοσης Sci Rep (2018)

A novel systemically administered toll-like receptor 7 agonist potentiates the effect of ionizing radiation in murine solid tumor models

ανά Adlard, Amy L, Dovedi, Simon J, Telfer, Brian A, Koga-Yamakawa, Erina, Pollard, Charlotte, Honeychurch, Jamie, Illidge, Timothy M, Murata, Masashi, Robinson, David T, Jewsbury, Philip J, Wilkinson, Robert W, Stratford, Ian J
Τόπος έκδοσης Int J Cancer (2014)

Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell–mediated immunotherapy

ανά Silk, Jonathan D., Hermans, Ian F., Gileadi, Uzi, Chong, Tsung Wen, Shepherd, Dawn, Salio, Mariolina, Mathew, Bini, Schmidt, Richard R., Lunt, Sarah Jane, Williams, Kaye J., Stratford, Ian J., Harris, Adrian L., Cerundolo, Vincenzo
Έκδοση 2004

Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancer

ανά Latif, Ayşe, Chadwick, Amy L., Kitson, Sarah J., Gregson, Hannah J., Sivalingam, Vanitha N., Bolton, James, McVey, Rhona J., Roberts, Stephen A., Marshall, Kay M., Williams, Kaye J., Stratford, Ian J., Crosbie, Emma J.
Τόπος έκδοσης BMC Clin Pathol (2017)

Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination...

ανά Dovedi, Simon J., Adlard, Amy L., Ota, Yosuke, Murata, Masashi, Sugaru, Eiji, Koga-Yamakawa, Erina, Eguchi, Ken, Hirose, Yuko, Yamamoto, Setsuko, Umehara, Hiroki, Honeychurch, Jamie, Cheadle, Eleanor J., Hughes, Gareth, Jewsbury, Philip J., Wilkinson, Robert W., Stratford, Ian J., Illidge, Timothy M.
Τόπος έκδοσης Oncotarget (2016)

Expression of NAD(P)H quinone dehydrogenase 1 (NQO1) is increased in the endometrium of women with endometrial cancer and women with polycystic ovary syndrome

ανά Atiomo, William, Shafiee, Mohamad Nasir, Chapman, Caroline, Metzler, Veronika M., Abouzeid, Jad, Latif, Ayşe, Chadwick, Amy, Kitson, Sarah, Sivalingam, Vanitha N., Stratford, Ian J., Rutland, Catrin S., Persson, Jenny L., Ødum, Niels, Fuentes‐Utrilla, Pablo, Jeyapalan, Jennie N., Heery, David M., Crosbie, Emma J., Mongan, Nigel P.
Τόπος έκδοσης Clin Endocrinol (Oxf) (2017)